I don't drive at all (because I never learned how, due to my phobia of it), so you have my empathy there.
I didn't have an office job immediately before the pandemic...but if I did, I think I'd also feel extreme anxiety about the prospect of going back, in much the same way you do.
Thank you for your honest dialogue of the issues facing so many of us within the disability community (as well as adding the intersection of anti-trans discrimination, for the educational benefit of myself and other cis folks).